The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, Second Edition
Винд Г. Дж.
At the beginning of the 21st century, medicine is increasingly based on understanding the functions of genes and the molecular mechanisms of diseases. In pancreatology, the understanding of functions and dysfunctions of the exocrine and endocrine pancreas is derived from molecular biological data on the actions of compounds in subcellular compartments and intracellular transcription pathways. In clinical medicine new and improved technical devices enable the gastroenterologist and the gastrointestinal surgeon to identify lesions by high-resolution imaging techniques, imaging of metabolic processes, and intrapancreatic ductal investigations. Decision making is increasingly based on the evidence of data from clinical trials on treatment modalities of pancreatic lesions.
Well into the 20th century the pancreas was considered a hidden organ. Now, at
the beginning of the 21st century, only ductal pancreatic cancer remains largely
an uncontrollable mystery disease. Today, understanding the pancreas, its normal
and abnormal functions, and its morphological pathology has become an international
focus of established scientists. Medical sciences are not uniform around the world.
However, the impact of information technology, international data exchange, and
global communications networks have resulted in a broadly increased level in the
understanding and practice of pancreatology. The synergistic interaction of basic
scientists, gastroenterologists, and gastrointestinal-tract surgeons in the field
of investigative and clinical pancreatology has led to better understanding of pancreatic
diseases through combining the knowledge of each to achieve the best evidence-based
management. Although care of patients cannot be made a global affair, this book
brings the most recent knowledge on the pancreas from international experts to readers
The goal of this second edition of The Pancreas - An Integrated Textbook of Basic
Science, Medicine, and Surgery is to provide the clinician with the most current
data-based synthesis of understanding of pancreatic diseases, functional assessments,
diagnostic and technical devices, and treatment options. A major part of this edition
has been contributed by leading international basic scientists, who provide an understanding
of the molecular basis of pancreatic functions and diseases.